Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Biostatistics
How to Cite
Endrenyi, L. 2005. Bioequivalence. Encyclopedia of Biostatistics. 1.
- Published Online: 15 JUL 2005
Bioequivalence is defined as the comparable bioavailability of alternative drug formulations. Kinetic measures of bioavailability are reviewed, leading to a discussion of the statistical assessment of bioequivalence. Parametric and nonparametric methods of testing are described. Current research areas including the estimation of individual bioequivalence and alternative measures for the evaluation of bioequivalence are reviewed.
- kinetic measures;
- area under the curve (AUC);
- individual bioequivalence