Published Online: 15 JUL 2005
Copyright © 2005 John Wiley & Sons, Ltd
Encyclopedia of Biostatistics
How to Cite
Majumder, P. P. 2005. Admixture Mapping. Encyclopedia of Biostatistics. 1.
- Published Online: 15 JUL 2005
Admixture between populations leads to linkage disequilibrium between loci if the allele frequencies are different between populations. One can test whether the linkage disequilibrium is due to linkage or admixture. One can condition the analysis on parental genotype or parental admixture. In the former case, what is scored is whether a haplotype in a parent is transmitted or not to an affected offspring.
- linkage disequilibrium;
- transmission disequilibrium;
- population history;
- disease–marker association, haplotypes