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Aalen's Additive Regression Model

  1. Odd O. Aalen1,
  2. Thomas H. Scheike2

Published Online: 15 JUL 2005

DOI: 10.1002/0470011815.b2a11002

Encyclopedia of Biostatistics

Encyclopedia of Biostatistics

How to Cite

Aalen, O. O. and Scheike, T. H. 2005. Aalen's Additive Regression Model. Encyclopedia of Biostatistics. 1.

Author Information

  1. 1

    Section of Medical Statistics, University of Oslo, Oslo, Norway

  2. 2

    University of Copenhagen, Thomas Scheike, Department of Biostatistics, Copenhagen N, Denmark

Publication History

  1. Published Online: 15 JUL 2005

Abstract

In survival analysis, the well-known Cox regression is based on modeling the hazard rate. This method assumes a proportional hazard structure. Aalen's additive model, however, assumes a linear parametric structure on the hazard rate. This approach may be justified within counting process theory, and produces martingale type estimates. These are used for plotting purposes and shows time-varying effects of covariates on survival. The plots are easy to compute and have a well-developed statistical theory. There exist several software packages for carrying out the analysis.

Keywords:

  • survival analysis;
  • hazard rate;
  • counting process;
  • regression model;
  • nonparametric