Chapter 8. Probabilistic Approaches to Aggregate and Cumulative Risk Assessment

  1. Claire A. Franklin2 and
  2. John P. Worgan3
  1. Robert L. Sielken Jr

Published Online: 22 AUG 2005

DOI: 10.1002/0470012218.ch8

Occupational and Residential Exposure Assessment for Pesticides

Occupational and Residential Exposure Assessment for Pesticides

How to Cite

Sielken, R. L. (2005) Probabilistic Approaches to Aggregate and Cumulative Risk Assessment, in Occupational and Residential Exposure Assessment for Pesticides (eds C. A. Franklin and J. P. Worgan), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470012218.ch8

Editor Information

  1. 2

    Pest Management Regulatory Agency, Health Canada, Sir Charles Tupper Building, 2250 Riverside Drive, Postal Locator 6604D, Ottawa and the R. Samuel McLaughlin Centre for Population Health Risk Assessment, Ottowa, Ontario, Canada

  2. 3

    Pest Management Regulatory Agency, Health Canada, Sir Charles Tupper Building, 2250 Riverside Drive, Postal Locator 6604D, Ottawa, ON K1A 0K9, Canada

Author Information

  1. Sielken & Associates Consulting, Inc., 3833 Texas Avenue, Suite 230, Bryan, TX 77802, USA

Publication History

  1. Published Online: 22 AUG 2005
  2. Published Print: 14 JAN 2005

Book Series:

  1. Wiley Series in Agrochemicals and Plant Protection

Book Series Editors:

  1. Terry Roberts4 and
  2. Junshi Miyamoto5

Series Editor Information

  1. 4

    Anglesey, UK

  2. 5

    Formerly of Sumitomo Chemical Ltd, Japan

ISBN Information

Print ISBN: 9780471489894

Online ISBN: 9780470012215

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Keywords:

  • aggregate and cumulative assessments of exposure;
  • probabilistic risk assessment methods;
  • Cumulative and Aggregate Risk Evaluation System (CARES);
  • risk characterization;
  • total margin of exposure (Total MOE);
  • dose–response relationships;
  • margins of exposure;
  • Monte Carlo simulation;
  • toxic equivalence factors (TEFs)

Summary

This chapter contains sections titled:

  • Introduction

  • Overview of Aggregate and Cumulative Risk Assessment

  • Characterizing Dose and Risk in a Cumulative Assessment

  • Case Study

  • Benefits of Using Probabilistic Techniques Instead of Default Constants

  • Probabilistic Exposure Characterization

  • Populations of Individuals

  • Conclusions and Recommendations

  • References