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Chapter 10. Aptamers: Powerful Molecular Tools for Therapeutics and Diagnostics

  1. Ralph Rapley3,
  2. Stuart Harbron4
  1. Eva Baldrich Rubio1,
  2. Mònica Campàs i Homs1,
  3. Ciara K. O'Sullivan2

Published Online: 27 SEP 2005

DOI: 10.1002/0470020202.ch10

Molecular Analysis and Genome Discovery

Molecular Analysis and Genome Discovery

How to Cite

Baldrich Rubio, E., Homs, M. C. i. and O'Sullivan, C. K. (2005) Aptamers: Powerful Molecular Tools for Therapeutics and Diagnostics, in Molecular Analysis and Genome Discovery (eds R. Rapley and S. Harbron), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470020202.ch10

Editor Information

  1. 3

    University of Hertfordshire, UK

  2. 4

    The Enzyme Technology Consultancy, UK

Author Information

  1. 1

    Department of Chemical Engineering, Universitat Rovira i Virgili, Avinguda Paisos Catalans 26, 43007 Tarragona, Spain

  2. 2

    Department of Chemical Engineering. Universitat Rovira i Virgili, Avinguda Paisos Catalans 26, 43007 Tarragona, Spain, and Institució Catalana de Recerca i Estudis Avancats, Passeig Lluis Companys 23, 08010 Barcelona, Spain

Publication History

  1. Published Online: 27 SEP 2005
  2. Published Print: 23 APR 2004

ISBN Information

Print ISBN: 9780471499190

Online ISBN: 9780470020203

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Keywords:

  • SELEX;
  • aptamers;
  • deoxynucleoside triphosphates (cNTPs);
  • spiegelmers;
  • intramers;
  • staphylococcal enterotoxin B (SEB);
  • affinity probe capillary electrophoresis (APCE);
  • aptasensors;
  • molecular beacons

Summary

This chapter contains sections titled:

  • Introduction

  • Aptamer selection

  • Aptamers for therapeutics

  • Aptamers in analysis

  • Aptamers for proteomic applications

  • Perspectives and future outlook

  • Acknowledgements

  • Abbreviations

  • References