Chapter 14. Structure-Based Drug Discovery
- Ralph Rapley3,
- Stuart Harbron4
Published Online: 27 SEP 2005
DOI: 10.1002/0470020202.ch14
Copyright © 2004 John Wiley & Sons, Ltd
Book Title
Molecular Analysis and Genome Discovery
Additional Information
How to Cite
Kan, C.-C., Hambly, K. and Debe, D. A. (2005) Structure-Based Drug Discovery, in Molecular Analysis and Genome Discovery (eds R. Rapley and S. Harbron), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470020202.ch14
Editor Information
- 3
University of Hertfordshire, UK
- 4
The Enzyme Technology Consultancy, UK
Publication History
- Published Online: 27 SEP 2005
- Published Print: 23 APR 2004
ISBN Information
Print ISBN: 9780471499190
Online ISBN: 9780470020203
- Summary
- Chapter
Keywords:
- drug discovery;
- dihydrofolate reductase (DHFR);
- Chinese Hamster Ovary (CHO);
- X-ray crystallography;
- inosine monophosphate dehydrogenase (IMPDH);
- computational structural proteomics
Summary
This chapter contains sections titled:
Overview of drug discovery and development
Principles of structure-based drug discovery
Case studies of structure-based drug discovery
Structure-based drug discovery in the post-genomic era
Acknowledgements
References