Chapter 4. An Overview of Genotyping and Single Nucleotide Polymorphisms (SNP)
- Ralph Rapley2,
- Stuart Harbron3
Published Online: 27 SEP 2005
DOI: 10.1002/0470020202.ch4
Copyright © 2004 John Wiley & Sons, Ltd
Book Title
Molecular Analysis and Genome Discovery
Additional Information
How to Cite
Gut, I. G. (2005) An Overview of Genotyping and Single Nucleotide Polymorphisms (SNP), in Molecular Analysis and Genome Discovery (eds R. Rapley and S. Harbron), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470020202.ch4
Editor Information
- 2
University of Hertfordshire, UK
- 3
The Enzyme Technology Consultancy, UK
Publication History
- Published Online: 27 SEP 2005
- Published Print: 23 APR 2004
ISBN Information
Print ISBN: 9780471499190
Online ISBN: 9780470020203
- Summary
- Chapter
Keywords:
- single nucleotide polymorphisms;
- quantitative trait loci (QTL);
- short tandem repeats – STRs;
- dynamic allele-specific hybridization (DASH);
- primer extension;
- oligonucleotide ligation (OLA);
- arrayed primer extension (APEX);
- haplotypes;
- restriction fragment length polymorphism (RFLP)
Summary
This chapter contains sections titled:
Introduction
Genotyping of single nucleotide polymorphisms
Methods for interrogating SNPs
Analysis formats
How can SNP genotyping be made more economic? Miniaturization – Multiplexing
Haplotyping
DNA methylation analysis – analysis of methylation variable positions (MVPs)
SNP genotyping and quantitation
Emerging methods
High-throughput SNP genotyping methods
The next generation
Conclusions
Acknowledgements
References