4. Metabolic Modeling Analysis of Brain Metabolism

  1. Robert G. Shulman2 and
  2. Douglas L. Rothman3
  1. Graeme Mason

Published Online: 18 AUG 2005

DOI: 10.1002/0470020520.ch4

Brain Energetics and Neuronal Activity: Applications to fMRI and Medicine

Brain Energetics and Neuronal Activity: Applications to fMRI and Medicine

How to Cite

Mason, G. (2004) Metabolic Modeling Analysis of Brain Metabolism, in Brain Energetics and Neuronal Activity: Applications to fMRI and Medicine (eds R. G. Shulman and D. L. Rothman), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470020520.ch4

Editor Information

  1. 2

    Yale University School of Medicine, MR Center, P.O. Box 208043, New Haven, CT 06520-8043, USA

  2. 3

    Department of Diagnostic Radiology, Yale University School of Medicine, MR Center, P.O. Box 208043, New Haven, CT 06520-8043, USA

Author Information

  1. Department of Psychiatry, Yale University School of Medicine, MR Center, P.O. Box 208043, New Haven, CT 06520-8043, USA

Publication History

  1. Published Online: 18 AUG 2005
  2. Published Print: 29 MAR 2004

ISBN Information

Print ISBN: 9780470847206

Online ISBN: 9780470020524

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Keywords:

  • metabolic model;
  • metabolic pools;
  • Michaelis–Menten kinetics;
  • combination Pools;
  • target data;
  • isotopomers;
  • least-squares Fitting

Summary

This chapter contains sections titled:

  • Introduction

  • Basic Elements of a Metabolic Model for 13C NMR Studies

  • Uniting the Elements to Create a Model

  • Mechanics of Fitting Data

  • Conclusion

  • References