Chapter 18. Bioorganosilicon Chemistry

  1. Saul Patai Professor and
  2. Zvi Rappoport
  1. Reinhold Tacke and
  2. Haryanto Linoh

Published Online: 10 AUG 2004

DOI: 10.1002/0470025107.ch18

Organic Silicon Compounds Volume 1 and Volume 2 (1989)

Organic Silicon Compounds Volume 1 and Volume 2 (1989)

How to Cite

Tacke, R. and Linoh, H. (1989) Bioorganosilicon Chemistry, in Organic Silicon Compounds Volume 1 and Volume 2 (1989) (eds S. Patai and Z. Rappoport), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470025107.ch18

Editor Information

  1. The Hebrew University, Jerusalem, Israel

Author Information

  1. Institut für Anorganische und Analytische Chemie, Technische Universität Braunschweig, D-3300 Braunschweig, FRG, Germany

Publication History

  1. Published Online: 10 AUG 2004
  2. Published Print: 25 JAN 1989

Book Series:

  1. PATAI'S Chemistry of Functional Groups

Book Series Editors:

  1. Saul Patai

Series Editor Information

  1. The Hebrew University, Jerusalem, Israel

ISBN Information

Print ISBN: 9780471919933

Online ISBN: 9780470025109

SEARCH

Summary

This chapter contains sections titled:

  • Introduction

  • Syntheses and Pharmacological Properties of Organosilicon Compounds

    • Introduction

    • Silyl Derivatives of Known Drugs

      • O and N Silylation

      • C Silylation

    • Bioactive Organosilicon Compounds without Carbon Analogues

      • Introduction

      • Silatranes

      • Silanols and Siloxanes

      • Miscellaneous Types of Compounds

    • Sila-substitution of Drugs

      • Introduction

      • C/Si Pairs of the Type (≡C)4C/(≡C)4Si

      • C/Si Pairs of the Type (≡C)3C[BOND]OC≡/(≡C)3Si[BOND]OC≡

      • C/Si Pairs of the Type (≡C)3C[BOND]H/(≡C)3Si[BOND]H

      • C/Si Pairs of the Type (≡C)3C[BOND]OH/(≡C)3Si[BOND]OH

      • C/Si Pairs of the Types R1R2R3CH/R1R2R3SiCH3 and R1R2CH2/R1R2Si(CH3)2

      • Conclusions

  • Toxicological Properties of Organosilicon Compounds

  • Metabolic Fate of Organosilicon Compounds

  • Organosilicon Perfumes

  • Biotransformations of Organosilicon Compounds Using Whole Microorganisms or Isolated Enzymes

  • Concluding Remarks

  • Acknowledgements

  • References