Chapter 2. Origin of Life and the First Signalling Molecules

  1. David A. Lovejoy Associate Professor of Zoology

Published Online: 20 DEC 2005

DOI: 10.1002/0470027878.ch2

Neuroendocrinology: An Integrated Approach

Neuroendocrinology: An Integrated Approach

How to Cite

Lovejoy, D. A. (2005) Origin of Life and the First Signalling Molecules, in Neuroendocrinology: An Integrated Approach, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470027878.ch2

Author Information

  1. University of Toronto, Toronto, Canada

Publication History

  1. Published Online: 20 DEC 2005
  2. Published Print: 8 JUL 2005

ISBN Information

Print ISBN: 9780470844328

Online ISBN: 9780470027875



  • living system;
  • last universal common ancestor (LUCA);
  • metabolism and replication;
  • self-catalysing networks;
  • Metabolic Channelling concept;
  • first signalling systems;
  • biotic world and non-biotic world;
  • evolution of metabolism and signalling;
  • intercellular chemical communication system


This chapter contains sections titled:

  • Introduction

  • Theories of the evolution of the first cells

  • The first cells

  • The first true signalling molecules

  • Chapter summary