12. Zinc Metalloneurochemistry: Physiology, Pathology, and Probes

  1. Astrid Sigel2,
  2. Helmut Sigel2 and
  3. Roland K. O. Sigel3
  1. Christopher J. Chang and
  2. Stephen J. Lippard

Published Online: 27 JUL 2006

DOI: 10.1002/0470028114.ch12

Neurodegenerative Diseases and Metal Ions, Volume 1

Neurodegenerative Diseases and Metal Ions, Volume 1

How to Cite

Chang, C. J. and Lippard, S. J. (2006) Zinc Metalloneurochemistry: Physiology, Pathology, and Probes, in Neurodegenerative Diseases and Metal Ions, Volume 1 (eds A. Sigel, H. Sigel and R. K. O. Sigel), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470028114.ch12

Editor Information

  1. 2

    Department of Chemistry, Inorganic Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

  2. 3

    Institute of Inorganic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Author Information

  1. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA

Publication History

  1. Published Online: 27 JUL 2006
  2. Published Print: 24 MAR 2006

ISBN Information

Print ISBN: 9780470014882

Online ISBN: 9780470028117

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Keywords:

  • zinc in brain;
  • transport, trafficking and homeostasis;
  • zinc sensing in neuroscience application;
  • zinc detection methods;
  • biomolecule fluorescent probe for zinc;
  • small-molecule fluorescent probe for zinc;
  • dansyl ionophores;
  • intensity-based fluorescent sensors;
  • fluorescent sensor in ratiometric zinc detection

Summary

This chapter contains sections titled:

  • Introduction

  • Zinc in the Brain

  • Zinc Sensing for Neuroscience Applications

  • Biomolecule Fluorescent Probes for Zinc

  • Small-Molecule Fluorescent Probes for Zinc

  • Concluding Remarks and Future Directions

  • Acknowledgments

  • Abbreviations

  • References