Chapter 2. Antidepressants

  1. Jeffrey A. Lieberman M.D. Professor Chair1 and
  2. Allan Tasman M.D. Professor Chair2

Published Online: 3 JUL 2006

DOI: 10.1002/0470029439.ch2

Handbook of Psychiatric Drugs

Handbook of Psychiatric Drugs

How to Cite

Lieberman, J. A. and Tasman, A. (2006) Antidepressants, in Handbook of Psychiatric Drugs, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470029439.ch2

Author Information

  1. 1

    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, and Director, New York State Psychiatric Institute, New York, USA

  2. 2

    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky, USA

Publication History

  1. Published Online: 3 JUL 2006
  2. Published Print: 31 MAR 2006

ISBN Information

Print ISBN: 9780470028216

Online ISBN: 9780470029435



  • antidepressants in depression;
  • antidepressants and panic disorder (PD), obsessive–compulsive disorder (OCD);
  • antidepressants and bulimia and posttraumatic stress disorder (PTSD);
  • pharmacotherapy of depression;
  • pharmacokinetics of TCAs;
  • drug selection in major depressions;
  • therapeutic drug monitoring;
  • antidepressant drug augmentation;
  • cardiotoxicity of TCAs;
  • tricyclic antidepressants


This chapter contains sections titled:

  • Introduction

  • Pharmacology

  • Indications for Use of Antidepressants

  • Drug Selection and Initiation of Treatment for Major Depression

  • Treatment of Partially Responsive and Nonresponsive Patients

  • Side Effects

  • Drug Interactions

  • Summary

  • Additional Reading