Chapter 6. Computer Simulation of Tumour Response to Therapy

  1. Sylvia Nagl
  1. Georgios S. Stamatakos and
  2. Nikolaos Uzunoglu

Published Online: 16 MAY 2006

DOI: 10.1002/0470032898.ch6

Cancer Bioinformatics: From Therapy Design to Treatment

Cancer Bioinformatics: From Therapy Design to Treatment

How to Cite

Stamatakos, G. S. and Uzunoglu, N. (2006) Computer Simulation of Tumour Response to Therapy, in Cancer Bioinformatics: From Therapy Design to Treatment (ed S. Nagl), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470032898.ch6

Editor Information

  1. Department of Oncology, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK

Author Information

  1. In Silico Oncology Group, Microwave and Fiber Optics Laboratory, Institute of Communication and Computer Systems, School of Electrical and Computer Engineering, National Technical University of Athens, 9 Iroon Polytechniou St., 15780 Zografos, Greece

Publication History

  1. Published Online: 16 MAY 2006
  2. Published Print: 27 JAN 2006

ISBN Information

Print ISBN: 9780470863046

Online ISBN: 9780470032893

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Keywords:

  • mathematical analysis and discrete mathematics;
  • computer simulation efforts;
  • finite difference time domain (FDTD) technique;
  • radiotherapy response simulation;
  • tumour simulation models;
  • DNA and protein microarrays;
  • chemotherapy response simulation;
  • efficacy–toxicity mathematical model;
  • tumour vulnerability identification

Summary

This chapter contains sections titled:

  • Introduction

  • Tumour growth simulation

  • Radiotherapy response simulation

  • Chemotherapy response simulation

  • Simulation of tumour response to other therapeutic modalities

  • Simulation of normal tissue response to antineoplastic interventions

  • Integration of molecular networks into tumour behaviour simulations

  • Future directions