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Chapter 16. Imaging the Effects of Vasculature-targeting Agents

  1. Dietmar W. Siemann2,3
  1. Susan M. Galbraith

Published Online: 31 MAY 2006

DOI: 10.1002/0470035439.ch16

Vascular-Targeted Therapies in Oncology

Vascular-Targeted Therapies in Oncology

How to Cite

Galbraith, S. M. (2006) Imaging the Effects of Vasculature-targeting Agents, in Vascular-Targeted Therapies in Oncology (ed D. W. Siemann), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470035439.ch16

Editor Information

  1. 2

    Shands Cancer Center, University of Florida, Gainsville, Florida, USA

  2. 3

    Research Department of Radiation Oncology, University of Florida, 2000 RW Archer Road, Gainsville, FL 32610, USA

Author Information

  1. Bristol-Myers Squibb, Clinical Discovery – Oncology, Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ 08543-4000, USA

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 10 MAR 2006

ISBN Information

Print ISBN: 9780470012949

Online ISBN: 9780470035436

SEARCH

Keywords:

  • imaging effect of vascular-targeting agents;
  • imaging tissue blood flow rate;
  • central volume theorem;
  • Kety model;
  • Color Doppler ultrasonography;
  • imaging hypoxia;
  • imaging glucose metabolism;
  • dose– and exposure–response relationships

Summary

This chapter contains sections titled:

  • Introduction

  • Methods for imaging tissue blood flow rate

  • Central volume theorem

  • Kety model

  • Fraction of cardiac output or ‘first-pass’ methods

  • Color Doppler ultrasonography

  • Imaging hypoxia

  • Imaging glucose metabolism

  • Preclinical experience of imaging vascular-disrupting agents

  • Clinical experience of imaging vascular-disrupting agents

  • Conclusions

  • References