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Chapter 7. Combined Modality Approaches Using Vasculature-disrupting Agents

  1. Dietmar W. Siemann3,4
  1. Wenyin Shi1,
  2. Michael R. Horsman2,
  3. Dietmar W. Siemann3,4

Published Online: 31 MAY 2006

DOI: 10.1002/0470035439.ch7

Book Title

Vascular-Targeted Therapies in Oncology

Vascular-Targeted Therapies in Oncology

Additional Information

How to Cite

Shi, W., Horsman, M. R. and Siemann, D. W. (2006) Combined Modality Approaches Using Vasculature-disrupting Agents, in Vascular-Targeted Therapies in Oncology (ed D. W. Siemann), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470035439.ch7

Editor Information

  1. 3

    Shands Cancer Center, University of Florida, Gainsville, Florida, USA

  2. 4

    Research Department of Radiation Oncology, University of Florida, 2000 RW Archer Road, Gainsville, FL 32610, USA

Author Information

  1. 1

    Department of Radiation Oncology, University of Florida, Shands Cancer Center, Gainsville, FL 32610, USA

  2. 2

    Department of Experimental Clinical Oncology, Aarhus University Hospital, Noerrebrogade 44, Building 5, 8000 Aarhus C, Denmark

  3. 3

    Shands Cancer Center, University of Florida, Gainsville, Florida, USA

  4. 4

    Research Department of Radiation Oncology, University of Florida, 2000 RW Archer Road, Gainsville, FL 32610, USA

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 10 MAR 2006

ISBN Information

Print ISBN: 9780470012949

Online ISBN: 9780470035436

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CHAPTER TOOLS

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Keywords:

  • vascular disrupting agents (VDAs) - DMXAA, CA4DP, ZD6126 and OXi4503;
  • tumor vasculature;
  • combined modality approaches;
  • inhibiting tumor-initiated angiogenic process;
  • destroying existing tumor vasculature;
  • vascular-disrupting strategies;
  • VDAs and chemotherapy;
  • VDAs and radiation therapy;
  • VDAs and antiangiogenic agents

Summary

This chapter contains sections titled:

  • Tumor vasculature

  • Vascular-disrupting strategies

  • VDAs and chemotherapy

  • VDAs and radiation therapy

  • VDAs and antiangiogenic agents

  • Summary

  • Acknowledgments

  • References

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