Chapter 21. Computer Simulations in Pharmacokinetics and Pharmacodynamics: Rediscovering Systems Physiology in the 21st Century

  1. Sean Ekins M.SC., PH.D., D.SC.
  1. Paolo Vicini

Published Online: 5 JUN 2006

DOI: 10.1002/0470037237.ch21

Computer Applications in Pharmaceutical Research and Development

Computer Applications in Pharmaceutical Research and Development

How to Cite

Vicini, P. (2006) Computer Simulations in Pharmacokinetics and Pharmacodynamics: Rediscovering Systems Physiology in the 21st Century, in Computer Applications in Pharmaceutical Research and Development (ed S. Ekins), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/0470037237.ch21

Editor Information

  1. 601 Runnymede Ave., Jenkintown, PA 19046., USA

Author Information

  1. Resource Facility for population kinetics, Room 241 AERL Building, Department of Bioengineering, Box 352255, University of Washington, Seattle, WA 98195-2255, USA

Publication History

  1. Published Online: 5 JUN 2006
  2. Published Print: 14 JUL 2006

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780471737797

Online ISBN: 9780470037232

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Keywords:

  • computer simulation in cell;
  • rediscovering systems physiology in 21st century;
  • biocomputation developments in drug development

Summary

This chapter contains sections titled:

  • Introduction

  • Level 1: Computer Simulation of the Whole Organism

  • Level 2: Computer Simulation of Isolated Tissues and Organs

  • Level 3: Computer Simulations of the Cell

  • Level 4: Proteins and Genes

  • Conclusion

  • Acknowledgments

  • References