Chapter 4. Understanding Protein Interactions and Their Representation in the Gas Phase of the Mass Spectrometer

  1. Julia Laskin PhD3 and
  2. Chava Lifshitz PhD4
  1. Frank Sobott1 and
  2. Carol V. Robinson2

Published Online: 6 MAR 2006

DOI: 10.1002/047005042X.ch4

Principles of Mass Spectrometry Applied to Biomolecules

Principles of Mass Spectrometry Applied to Biomolecules

How to Cite

Sobott, F. and Robinson, C. V. (2006) Understanding Protein Interactions and Their Representation in the Gas Phase of the Mass Spectrometer, in Principles of Mass Spectrometry Applied to Biomolecules (eds J. Laskin and C. Lifshitz), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/047005042X.ch4

Editor Information

  1. 3

    Fundamental Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999 K8-88, Richland, WA 99352, USA

  2. 4

    Department of Physical Chemistry and The Farkas Center for Light Induced Processes, The Hebrew University of Jerusalem, Jerusalem 91904, Israel

Author Information

  1. 1

    Structural Genomics Consortium, University of Oxford, Botnar Research Centre, Oxford OX3 7LD, United Kingdom

  2. 2

    The University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom

Publication History

  1. Published Online: 6 MAR 2006
  2. Published Print: 16 OCT 2006

ISBN Information

Print ISBN: 9780471721840

Online ISBN: 9780470050422

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Keywords:

  • understanding protein interactions and their representation;
  • biomolecule electrospray mass spectrometry;
  • ion transmission and noncovalent complex analysis

Summary

This chapter contains sections titled:

  • Protein Structure and Interactions in Mass Spectrometry

  • Electrospray Mass Spectrometry of Biomolecules

  • Ion Transmission and Analysis of Noncovalent Complexes

  • Some Examples

  • Challenges and Future Directions

  • Acknowledgments

  • References