Chapter 15. Development of Radiolabeled Probes to Monitor Gene Therapy

  1. Michael J. Welch3 and
  2. Carol S. Redvanly4
  1. Chyng-Yann Shiue1 and
  2. Stephen L. Eck2

Published Online: 28 JAN 2005

DOI: 10.1002/0470846380.ch15

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

How to Cite

Shiue, C.-Y. and Eck, S. L. (2002) Development of Radiolabeled Probes to Monitor Gene Therapy, in Handbook of Radiopharmaceuticals: Radiochemistry and Applications (eds M. J. Welch and C. S. Redvanly), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470846380.ch15

Editor Information

  1. 3

    Washington University School of Medicine, Mallinckrodt Institute of Radiology, 510 S. Kingshighway Boulevard, Campus Box 8225, St. Louis, MO, USA

  2. 4

    Department of Chemistry, Brookhaven National Laboratory Associated Universities Ltd, Upton, New York, USA

Author Information

  1. 1

    Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, USA

  2. 2

    Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 27 NOV 2002

ISBN Information

Print ISBN: 9780471495604

Online ISBN: 9780470846384

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Keywords:

  • gene therapy;
  • reporter genes and reporter probes;
  • RASON probe

Summary

This chapter contains sections titled:

  • Introduction

  • Reporter Gene

  • Reporter Probes

  • Comparison of Uracil and Acycloguanosine Analogs As Gene Expression Imaging Agents

  • Conclusion

  • Acknowledgement

  • References