Chapter 4. Chemistry of Nitrogen-13 and Oxygen-15

  1. Michael J. Welch2 and
  2. Carol S. Redvanly3
  1. John C. Clark and
  2. Franklin I. Aigbirhio

Published Online: 28 JAN 2005

DOI: 10.1002/0470846380.ch4

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

How to Cite

Clark, J. C. and Aigbirhio, F. I. (2002) Chemistry of Nitrogen-13 and Oxygen-15, in Handbook of Radiopharmaceuticals: Radiochemistry and Applications (eds M. J. Welch and C. S. Redvanly), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470846380.ch4

Editor Information

  1. 2

    Washington University School of Medicine, Mallinckrodt Institute of Radiology, 510 S. Kingshighway Boulevard, Campus Box 8225, St. Louis, MO, USA

  2. 3

    Department of Chemistry, Brookhaven National Laboratory Associated Universities Ltd, Upton, New York, USA

Author Information

  1. Wolfson Brain Imaging Centre, University of Cambridge, Box 65, Addenbrooke's Hospital, Cambridge, CB2 2QQ, United Kingdom

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 27 NOV 2002

ISBN Information

Print ISBN: 9780471495604

Online ISBN: 9780470846384

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Keywords:

  • positron-emitting isotopes;
  • nitrogen-13 and oxygen-15;
  • radiotracer delivery and management systems

Summary

This chapter contains sections titled:

  • Introduction

  • The Chemistry of Nitrogen-13

  • Production of Nitrogen-13

  • Nitrogen-13 Labeled Amino Acids

  • Nitrogen-13 Labelled Amines

  • Other Nitrogen-13 Radiotracers

  • Quality Assurance Methods for [13N]Ammonia

  • The Chemistry of Oxygen-15

  • Production of Oxygen-15

  • Chemical Conversion of Primary in-target Produced Products

  • Quality Control of 15O Labelled Compounds

  • Radiotracer Delivery and Waste Management Systems

  • References