Chapter 9. Design and Synthesis of 2-Deoxy-2-[18F]Fluoro-D-Glucose (18FDG)

  1. Michael J. Welch2 and
  2. Carol S. Redvanly3
  1. Joanna S. Fowler3 and
  2. Tatsuo Ido1

Published Online: 28 JAN 2005

DOI: 10.1002/0470846380.ch9

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

Handbook of Radiopharmaceuticals: Radiochemistry and Applications

How to Cite

Fowler, J. S. and Ido, T. (2002) Design and Synthesis of 2-Deoxy-2-[18F]Fluoro-D-Glucose (18FDG), in Handbook of Radiopharmaceuticals: Radiochemistry and Applications (eds M. J. Welch and C. S. Redvanly), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470846380.ch9

Editor Information

  1. 2

    Washington University School of Medicine, Mallinckrodt Institute of Radiology, 510 S. Kingshighway Boulevard, Campus Box 8225, St. Louis, MO, USA

  2. 3

    Department of Chemistry, Brookhaven National Laboratory Associated Universities Ltd, Upton, New York, USA

Author Information

  1. 1

    Tohoku University, Sendai, Japan

  2. 3

    Department of Chemistry, Brookhaven National Laboratory Associated Universities Ltd, Upton, New York, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 27 NOV 2002

ISBN Information

Print ISBN: 9780471495604

Online ISBN: 9780470846384

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Keywords:

  • FDG for animal and human studies;
  • CIDG;
  • 18FDG

Summary

This chapter contains sections titled:

  • Introduction

  • Design of 18FDG: The Importance of C-2

  • First Synthesis of 18FDG for Animal and Human Studies

  • Improvements and a Major Milestone (1976-1986)

  • 18FDG Synthesis (1986-Present)

  • Outlook

  • Acknowledgment

  • References