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Organic Synthesis Using Metal-Mediated Coupling Reactions

  1. Felix E. Goodson,
  2. Melissa B. Cichowicz

Published Online: 15 MAR 2006

DOI: 10.1002/0470862106.ia281

Encyclopedia of Inorganic Chemistry

Encyclopedia of Inorganic Chemistry

How to Cite

Goodson, F. E. and Cichowicz, M. B. 2006. Organic Synthesis Using Metal-Mediated Coupling Reactions. Encyclopedia of Inorganic Chemistry. .

Author Information

  1. West Chester University of Pennsylvania, West Chester, PA, USA

Publication History

  1. Published Online: 15 MAR 2006

Abstract

This article provides an overview of the cross-coupling protocols most commonly used in organic synthesis. Particular emphasis is placed upon topics likely to be of interest to the inorganic chemist, namely, history, catalyst development, and mechanistic studies. While not a comprehensive review, this treatment is intended to provide the reader with a summary of some successful catalyst design strategies, methodological improvements, and mechanistic insights that have been achieved over the past 10 years.

Keywords:

  • cross coupling;
  • catalysis;
  • palladium;
  • nickel;
  • mechanism;
  • methodology