Standard Article

X-Ray Crystallography

  1. Jules Mitchell Guss

Published Online: 15 SEP 2010

DOI: 10.1002/0470862106.ia331

Encyclopedia of Inorganic Chemistry

Encyclopedia of Inorganic Chemistry

How to Cite

Guss, J. M. 2010. X-Ray Crystallography. Encyclopedia of Inorganic Chemistry. .

Author Information

  1. University of Sydney, School of Molecular Bioscience, Sydney, NSW, Australia

Publication History

  1. Published Online: 15 SEP 2010


X-ray crystallography is the most extensively practised and widely applicable technique for determining molecular structures. These may be relatively small coordination complexes or metalloproteins with masses exceeding 1000 kda. The accuracy of the structures may range from a few thousands of Ǻngstrom for a small molecules to a few tenths of an Ǻngstrom for a protein. The major limitation of the technique is the requirement for well-diffracting crystals.


  • crystallography;
  • proteins;
  • crystal structure;
  • refinement