Chapter 12. Predictive Functional Analysis of Polymorphisms: An Overview
- Michael R. Barnes1,
- Ian C. Gray2
Published Online: 22 MAY 2003
DOI: 10.1002/0470867302.ch12
Copyright © 2003 John Wiley & Sons, Ltd
Book Title
Bioinformatics for Geneticists
Additional Information
How to Cite
Barnes, M. R. (2003) Predictive Functional Analysis of Polymorphisms: An Overview, in Bioinformatics for Geneticists (eds M. R. Barnes and I. C. Gray), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470867302.ch12
Editor Information
- 1
Genetic Bioinformatics, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW, UK
- 2
Discovery Genetics, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW, UK
Publication History
- Published Online: 22 MAY 2003
- Published Print: 21 FEB 2003
ISBN Information
Print ISBN: 9780470843932
Online ISBN: 9780470867303
- Summary
- Chapter
Summary
This chapter contains sections titled:
Introduction
Principles of Predictive Functional Analysis of Polymorphisms
The Anatomy of Promoter Regions and Regulatory Elements
The Anatomy of Genes
Pseudogenes and Regulatory mRNA
Analysis of Novel Regulatory Elements and Motifs in Nucleotide Sequences
Functional Analysis on Non-synonymous Coding Polymorphisms
A Note of Caution on the Prioritization of In Silico Predictions for Further Laboratory Investigation
Conclusions
References