Chapter 9. Genetic Studies from Genomic Sequence

  1. Michael R. Barnes1 and
  2. Ian C. Gray2
  1. Michael R. Barnes

Published Online: 22 MAY 2003

DOI: 10.1002/0470867302.ch9

Bioinformatics for Geneticists

Bioinformatics for Geneticists

How to Cite

Barnes, M. R. (2003) Genetic Studies from Genomic Sequence, in Bioinformatics for Geneticists (eds M. R. Barnes and I. C. Gray), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/0470867302.ch9

Editor Information

  1. 1

    Genetic Bioinformatics, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW, UK

  2. 2

    Discovery Genetics, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW, UK

Author Information

  1. Genetic Bioinformatics, GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW, UK

Publication History

  1. Published Online: 22 MAY 2003
  2. Published Print: 21 FEB 2003

ISBN Information

Print ISBN: 9780470843932

Online ISBN: 9780470867303

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Summary

This chapter contains sections titled:

  • Introduction

  • Defining the Locus

  • Case Study 1: Identification and Extraction of a Genomic Sequence between Two Markers (Recommended Tool: UCSC Human Genome Browser (HGB))

  • Case Study 2: Checking the Integrity of a Genomic Sequence between Two Markers (Recommended Tools: UCSC HGB, NCBI Map View, NCBI EPCR)

  • Case Study 3: Definition of Known and Novel Genes Across a Genomic Region (Recommended Tools: Ensembl and HGB)

  • Case Study 4: Candidate Gene Selection – Building Biological Rationale Around Genes (Recommended Tools: HGB, Ensembl)

  • Case Study 5: Known and Novel Marker Identification (Recommended Tools: Ensembl, HGB, Map View, SNPper)

  • Case Study 6: Genetic/Physical Locus Characterization and Marker Panel Design (Recommended Tools: Ensembl, HGB and Map View)

  • Conclusions

  • References