UNIT 1.2 Statistical Approaches to the Design of Toxicology Studies

  1. Shayne C. Gad

Published Online: 1 MAY 2001

DOI: 10.1002/0471140856.tx0102s00

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Gad, S. C. 2001. Statistical Approaches to the Design of Toxicology Studies. Current Protocols in Toxicology. 00:1.2:1.2.1–1.2.18.

Author Information

  1. Gad Consulting Services, Raleigh, North Carolina

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: MAY 1999


Application of statistics to toxicological studies involves hypothesis testing, model fitting, and reduction of dimensionality. This unit reviews statistical approaches to data (i.e., descriptive statistics, experimental design, outliers and rounding of numbers, and specific applications) and includes a set of decision trees to assist in choosing the appropriate methods.