UNIT 3.6 Detecting Epigenetic Changes: DNA Methylation

  1. Limor Broday,
  2. Max Costa

Published Online: 1 MAY 2001

DOI: 10.1002/0471140856.tx0306s03

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Broday, L. and Costa, M. 2001. Detecting Epigenetic Changes: DNA Methylation. Current Protocols in Toxicology. 3:3.6:3.6.1–3.6.8.

Author Information

  1. New York University School of Medicine, New York, New York

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: FEB 2000


This unit provides protocols for assessing the state of DNA methylation, including assays for determining the overall DNA methylation levels, measuring DNA methyltranseferase (MTase) activity, determining gene-specific methylation and overall chromatin condensation patterns.