UNIT 4.7 Measurement of Carboxylesterase (CES) Activities

  1. Masakiyo Hosokawa1,
  2. Tetsuo Satoh2

Published Online: 1 FEB 2002

DOI: 10.1002/0471140856.tx0407s10

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Hosokawa, M. and Satoh, T. 2002. Measurement of Carboxylesterase (CES) Activities. Current Protocols in Toxicology. 10:4.7:4.7.1–4.7.14.

Author Information

  1. 1

    Chiba University, Chiba, Japan

  2. 2

    Biomedical Research Institute, Chiba, Japan

Publication History

  1. Published Online: 1 FEB 2002
  2. Published Print: NOV 2001


Measurement of Carboxylesterase (CES) Activities (Masakiyo Hosokawa, Chiba University, Chiba, Japan and Tetsuo Satoh, Biomedical Research Institute, Chiba, Japan). Mammalian carboxyesterase (CES) efficiently catalyzes the hydrolysis of a variety of ester- and amide-containing chemicals. CES is involved in detoxification or metabolic activation of various drugs, environmental toxicants, and carcinogens. This unit contains three protocols for measuring CES activities.