Unit

UNIT 5.3 Measurement of Disposition Half-Life, Clearance, and Residence Times

  1. Michael Mayersohn

Published Online: 1 MAY 2001

DOI: 10.1002/0471140856.tx0503s04

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Mayersohn, M. 2001. Measurement of Disposition Half-Life, Clearance, and Residence Times. Current Protocols in Toxicology. 4:5.3:5.3.1–5.3.29.

Author Information

  1. The University of Arizona, Tucson, Arizona

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: MAY 2000

Abstract

This unit provides an overview of the principles underlying the elimination process. Experimental design issues, methods of data analysis, and complications that may be encountered are discussed. A complete worked example is provided to exemplify the methods of analysis that are available.