UNIT 6.10 Overview of Protein Glutathionylation
Published Online: 1 JUN 2006
Copyright © 2006 by John Wiley & Sons, Inc.
Lab Protocol Title
Current Protocols in Toxicology
How to Cite
Filipovska, A. and Murphy, M. P. 2006. Overview of Protein Glutathionylation. Current Protocols in Toxicology. 28:6.10:6.10.1–6.10.8.
- Published Online: 1 JUN 2006
- Published Print: MAY 2006
Many proteins contain free thiols that can be modified by the reversible formation of mixed disulfides with glutathione. Protein glutathionylation is of significance for defense against oxidative damage and in redox signaling. Here we outline the mechanisms and possible significance of protein glutathionylation.
- oxidative stress;
- protein thiols;
- redox regulation