UNIT 8.1 The Heme Biosynthesis Pathway and Clinical Manifestations of Abnormal Function
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Toxicology
How to Cite
Phillips, J. D. and Kushner, J. P. 2001. The Heme Biosynthesis Pathway and Clinical Manifestations of Abnormal Function. Current Protocols in Toxicology. 00:8.1:8.1.1–8.1.10.
- Published Online: 1 MAY 2001
- Published Print: MAY 1999
Biosynthesis of heme is important for both prokaryotes and eukaryotes. The enzymes for this multistep process are distributed between the cytosol and mitochondria in eukaryotes. In humans there are inherited and acquired disorders characterized by over synthesis of one or more enzymes or absence of an enzyme. This overview discusses each enzyme in the heme biosynthesis pathway.