UNIT 9.1 Overview of Heme Degradation Pathway
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Toxicology
How to Cite
Maines, M. D. 2001. Overview of Heme Degradation Pathway. Current Protocols in Toxicology. 00:9.1:9.1.1–9.1.5.
- Published Online: 1 MAY 2001
- Published Print: MAY 1999
Heme oxygenase 1 and 2 activities are responsible for initiating most of the degradation of heme, although other enzyme pathways play a role as well. The degradation pathway also includes biliverdin reductase, the activity of which is coupled to oxidation of NADH and NADPH. This overview discusses the pathways and enzymes involved in heme degradation.