UNIT 11.2 Neurobehavioral Screening in Rodents

  1. Virginia C. Moser

Published Online: 1 MAY 2001

DOI: 10.1002/0471140856.tx1102s06

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Moser, V. C. 2001. Neurobehavioral Screening in Rodents. Current Protocols in Toxicology. 00:11.2:11.2.1–11.2.16.

Author Information

  1. Apex, North Carolina

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: NOV 2000


Neurobehavioral evaluations are an important component of screening for neurotoxicological effects. A neurobehavioral test battery is chosen to assess a variety of endpoints, including autonomic, neuromuscular, sensory, and excitability functions. Such a battery includes observation of gait and posture, reactivity and arousal, gait and postural characteristics, involuntary/abnormal motor movements, clinical signs and manipulation of neurological reflexes and reactions and neuromuscular activity and postural reactions. Finally, the battery includes assessment of sensory responses.