UNIT 12.7 Isolation of Cerebellar Granule Cells from Neonatal Rats
Published Online: 1 NOV 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Toxicology
How to Cite
Oberdoerster, J. 2001. Isolation of Cerebellar Granule Cells from Neonatal Rats. Current Protocols in Toxicology. 9:12.7:12.7.1–12.7.10.
- Published Online: 1 NOV 2001
- Published Print: AUG 2001
Cerebellar Granule Cells in Neurotoxicology (Jan Oberdoerster, Aventis Corporation, Research Triangle Park, North Carolina). Cultured neurons allow the researcher to investigate mechanisms of toxicity on a relatively uniform population of cells. Primary cultures of cerebellar granule cells are post-mitotic neurons that are readily isolated and may be used for experimental procedures including electrophysiology, neuronal maturation, and various biochemical and molecular analyses.