Unit

UNIT 16.5 Monitoring Endocrine Function in Males: Using Intra-Atrial Cannulas to Monitor Plasma Hormonal Dynamics in Toxicology Experiments

  1. Patricia A. Fail,
  2. Stephanie A. Anderson

Published Online: 1 NOV 2002

DOI: 10.1002/0471140856.tx1605s13

Current Protocols in Toxicology

Current Protocols in Toxicology

How to Cite

Fail, P. A. and Anderson, S. A. 2002. Monitoring Endocrine Function in Males: Using Intra-Atrial Cannulas to Monitor Plasma Hormonal Dynamics in Toxicology Experiments. Current Protocols in Toxicology. 13:16.5:16.5.1–16.5.17.

Author Information

  1. Research Triangle Institute, Research Triangle Park, North Carolina

Publication History

  1. Published Online: 1 NOV 2002
  2. Published Print: AUG 2002

Abstract

Monitoring Endocrine Function in Males: Using an Intra-Atrial Cannula to Monitor Plasma Hormonal Dynamics in Toxicology Experiments (Patricia A. Fail and Stephanie A. Anderson, Research Triangle Institute, Research Triangle Park, North Carolina). Intra-atrial cannulation provides assessment of endocrine change within animals. Protocols for permanent tethers used in short-term 5- to 10-day experiments and permanent vascular access used in long-term (>10 days) experiments are presented. A protocol for blood processing is also included. Data from a longitudinal endocrine baseline assessment (LEBA) and an endocrine challenge test (ECT) a presented as well.