UNIT 2.3 Protein Secondary Structure Prediction

  1. Stanley R. Krystek Jr.,
  2. William J. Metzler,
  3. Jiri Novotny

Published Online: 1 MAY 2001

DOI: 10.1002/0471140864.ps0203s00

Current Protocols in Protein Science

Current Protocols in Protein Science

How to Cite

Krystek, S. R., Metzler, W. J. and Novotny, J. 2001. Protein Secondary Structure Prediction. Current Protocols in Protein Science. 00:2.3:2.3.1–2.3.20.

Author Information

  1. Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: JUN 1995


This unit describes procedures developed for predicting protein structure from the amino acid sequence. The first of the four sections is an overview and brief history of structure prediction schemes. The second section describes four distinct prediction schemes, with emphasis on their differences. In the third part each prediction scheme is used to evaluate three proteins that have different folding patterns. The final section is a comparison of the prediction results and suggestions for secondary structure prediction.