UNIT 2.8 Protein Tertiary Structure Modeling

  1. Nicolas Guex,
  2. Torsten Schwede,
  3. Manuel C. Peitsch

Published Online: 1 MAY 2001

DOI: 10.1002/0471140864.ps0208s23

Current Protocols in Protein Science

Current Protocols in Protein Science

How to Cite

Guex, N., Schwede, T. and Peitsch, M. C. 2001. Protein Tertiary Structure Modeling. Current Protocols in Protein Science. 23:2.8:2.8.1–2.8.17.

Author Information

  1. Glaxo Wellcome Experimental Research, Geneva, Switzerland

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: MAR 2001


Insights into the 3D-structure of a protein have proven useful during experiment design. Experimentally elucidated structures are often not available, but comparative protein modeling provides a viable alternative in many cases. This unit presents comparative protein modeling and how to use the highly sophisticated but easy-to-use free software available on the Internet.