Unit

UNIT 2.13 Protein Structure Analysis Online

  1. Maria A. Miteva1,
  2. Emil Alexov2,
  3. Bruno O. Villoutreix1

Published Online: 1 NOV 2007

DOI: 10.1002/0471140864.ps0213s50

Current Protocols in Protein Science

Current Protocols in Protein Science

How to Cite

Miteva, M. A., Alexov, E. and Villoutreix, B. O. 2007. Protein Structure Analysis Online. Current Protocols in Protein Science. 50:2.13:2.13.1–2.13.23.

Author Information

  1. 1

    Inserm U648, University of Paris, Paris, France

  2. 2

    Clemson University, South Carolina

Publication History

  1. Published Online: 1 NOV 2007
  2. Published Print: NOV 2007

Abstract

Computational biology/chemistry tools are used in most areas of life/health science research. These methods are continually being developed and their use can present difficulties for both experienced and novice investigators. To facilitate the use of these applications, many packages have been implemented online during these last 5 years. This unit focuses on online computational methods with a special emphasis on structural refinement/atomic simulations, protein electrostatic calculations, searches for functional sites, searches for druggable pockets, protein docking and small molecule docking, and prediction of potential impact of amino acid variations on the structure and function of the protein molecules. Curr. Protoc. Protein Sci. 50:2.13.1-2.13.23. © 2007 by John Wiley & Sons, Inc.

Keywords:

  • structural bioinformatics;
  • electrostatics;
  • simulations;
  • docking;
  • on-line tools;
  • druggable pocket