UNIT 7.8 Light Scattering

  1. Stephen E. Harding,
  2. Kornelia Jumel

Published Online: 1 MAY 2001

DOI: 10.1002/0471140864.ps0708s11

Current Protocols in Protein Science

Current Protocols in Protein Science

How to Cite

Harding, S. E. and Jumel, K. 2001. Light Scattering. Current Protocols in Protein Science. 11:7.8:7.8.1–7.8.14.

Author Information

  1. University of Nottingham School of Biology, Sutton, Bonington, United Kingdom

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: MAR 1998


Light scattering methods can provide information about the native molecular weight, oligomeric composition, and gross conformation of a protein in solution. These methods are particularly well suited for studying large oligomeric systems or glycoproteins and can be used to characterize much larger structures involving protein such as viruses and even bacterial spores. This overview discusses theory and application of both static and dynamic light scattering analysis of protein solutions.