UNIT 17.3 Principles of Macromolecular X-Ray Crystallography
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Protein Science
How to Cite
Hickman, A. B. and Davies, D. R. 2001. Principles of Macromolecular X-Ray Crystallography. Current Protocols in Protein Science. 10:17.3:17.3.1–17.3.15.
- Published Online: 1 MAY 2001
- Published Print: DEC 1997
X-ray crystallography is one of the major tools available for protein structural analysis. This unit provides an introductory review of the principles of X-ray crystallography that covers how the image is generated and analyzed. The second half of the unit describes strategies for producing crystals of protein, including methods for dealing with proteins that do not easily form crystals.