UNIT 20.3 Analytical Centrifugation: Equilibrium Approach
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Protein Science
How to Cite
Laue, T. 2001. Analytical Centrifugation: Equilibrium Approach. Current Protocols in Protein Science. 18:20.3:20.3.1–20.3.13.
- Published Online: 1 MAY 2001
- Published Print: DEC 1999
The specific interaction of biological molecules with one another is fundamental to the biochemistry of all living things. Equilibrium sedimentation is a classic method of biochemistry that provides first-principle thermodynamic information about the molar mass, association energy, association stoichiometry, and thermodynamic nonideality of molecules in solution. It is one of the most rigorous, powerful, and readily adapted methods for characterizing solution interactions.