UNIT 21.3 Overview of Pepsin-like Aspartic Peptidases
Published Online: 1 NOV 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Protein Science
How to Cite
Dunn, B. M. 2001. Overview of Pepsin-like Aspartic Peptidases. Current Protocols in Protein Science. 25:21.3:21.3.1–21.3.6.
- Published Online: 1 NOV 2001
- Published Print: SEP 2001
The aspartic peptidase family of enzymes has been implicated in a variety of disease states, from stomach ulcers, to breast cancer, and even Alzheimer's Disease. This unit describes the major characteristics of the aspartic peptidases, including mechanism of action, subcellular and tissue localization, and biological substrate specificity.