Unit

UNIT 29.1 Introduction to Membrane Proteins

  1. Mark L. Chiu

Published Online: 1 FEB 2012

DOI: 10.1002/0471140864.ps2901s67

Lab Protocol Title

Current Protocols in Protein Science

Current Protocols in Protein Science

Additional Information

How to Cite

Chiu, M. L. 2012. Introduction to Membrane Proteins. Current Protocols in Protein Science. 29:29.1:29.1.1–29.1.8.

Author Information

  1. Biologics Research, Biotechnology Center of Excellence, Janssen Research & Development, Radnor, Pennsylvania

Publication History

  1. Published Online: 1 FEB 2012
  2. Published Print: FEB 2012
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Abstract

Membrane proteins (MPs) mediate important physiological processes for the cell via extracellular and intracellular interactions. To better understand the biochemical and structural bases of these interactions, well-characterized preparations of purified MPs are required. This introduction reviews common problems encountered in MP preparation.

Keywords:

  • membrane protein;
  • purification and detergent solubilization;
  • protein stabilization
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