UNIT 1.7 Characterization of GABA Receptors
Published Online: 2 DEC 2013
Copyright © 2013 John Wiley & Sons, Inc. All rights reserved.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
Enna, S. and McCarson, K. E. 2013. Characterization of GABA Receptors. Current Protocols in Pharmacology. 63:1.7:1.7.1–1.7.20.
- Published Online: 2 DEC 2013
Described in this unit are ligand-binding assays for GABAA, GABAB, and the homomeric ρ GABAA (formerly GABAC) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS. These assays may also be used to determine the affinity of an unlabeled compound for the GABA binding sites. Excluded from the unit are ligand-binding assays for other components of the GABAA receptor complex, such as the benzodiazepine or ion-channel binding sites. Curr. Protoc. Pharmacol. 63:1.7.1-1.7.20. © 2013 by John Wiley & Sons, Inc.
- gamma amino butyric acid;
- ligand binding