UNIT 4.3 Isolated Cardiac Muscle Assays

  1. Terry Kenakin

Published Online: 1 MAY 2001

DOI: 10.1002/0471141755.ph0403s00

Current Protocols in Pharmacology

Current Protocols in Pharmacology

How to Cite

Kenakin, T. 2001. Isolated Cardiac Muscle Assays. Current Protocols in Pharmacology. 00:4.3:4.3.1–4.3.10.

Author Information

  1. Glaxo Wellcome Research And Development, Research Triangle Park, North Carolina

Publication History

  1. Published Online: 1 MAY 2001
  2. Published Print: MAR 1998


Isolated cardiac muscle is one of the major tissues used in pharmacological research. It is compact, easily prepared, and functions as a syncytium yielding rapid responses to a variety of agents. Described in this unit are methods of preparing and handling isolated cardiac muscle, a preparation rich in autonomic receptors.