UNIT 5.25 Overview of Animal Models of Asthma
Published Online: 1 MAY 2002
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
Canning, B. J. 2002. Overview of Animal Models of Asthma. Current Protocols in Pharmacology. 16:5.25:5.25.1–5.25.15.
- Published Online: 1 MAY 2002
- Published Print: MAR 2002
Asthma is an inflammatory disease characterized by airways obstruction, airways hyperresponsiveness, excessive mucous secretion and cough. Guinea pig airways display many anatomical, physiological and pharmacological attributes of human airways, making this species ideal for modeling the asthmatic condition. This unit provides an overview of animal models of asthma, including definitions, descriptions of available animal models, and discussion of numerous critical issues to consider before designing a model to study this complex disease.