UNIT 10.2 Models of Inflammation: Measuring Gastrointestinal Ulceration in the Rat
Published Online: 1 MAY 2001
Copyright © 2003 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
Whiteley, P. E. and Dalrymple, S. A. 2001. Models of Inflammation: Measuring Gastrointestinal Ulceration in the Rat. Current Protocols in Pharmacology. 00:10.2:10.2.1–10.2.4.
- Published Online: 1 MAY 2001
- Published Print: MAR 1998
In rats, nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin induce gastrointestinal ulcerations. This unit describes a procedure to elicit and measure indomethacin-induced gastrointestinal lesions. This approach can be used to test for gastrointestinal side effects of potential anti-inflammatory and other agents.