Unit

UNIT 11.10 Electrophysiology of Airway Nerves

  1. Allen C. Myers

Published Online: 1 DEC 2007

DOI: 10.1002/0471141755.ph1110s39

Current Protocols in Pharmacology

Current Protocols in Pharmacology

How to Cite

Myers, A. C. 2007. Electrophysiology of Airway Nerves. Current Protocols in Pharmacology. 39:11.10:11.10.1–11.10.27.

Author Information

  1. The Johns Hopkins University School of Medicine, Baltimore, Maryland

Publication History

  1. Published Online: 1 DEC 2007
  2. Published Print: DEC 2007

Abstract

Several different electrophysiological approaches have been used to study the pharmacology of the afferent, central, and efferent nervous systems in airways. This unit describes electrophysiological methods used to study nerves in these pathways and includes: (1) extracellular recording of afferent nerve activity in vivo and from the isolated airway in vitro, (2) intracellular and patch clamp recording of identified airway sensory neurons, (3) patch clamp recording of secondary afferent central nervous system neurons, (4) in vitro and in vivo intracellular recording of intact parasympathetic ganglionic neurons, and (5) patch recordings of dissociated parasympathetic ganglionic neurons. Curr. Protoc. Pharmacol. 39:11.10.1-11.10.27. © 2007 by John Wiley & Sons, Inc.

Keywords:

  • airway;
  • bronchus;
  • trachea;
  • afferent;
  • sensory;
  • parasympathetic