UNIT 12.5 Production and Use of HIV-1 Luciferase Reporter Viruses

  1. Carsten Münk,
  2. Nathaniel R. Landau

Published Online: 1 NOV 2003

DOI: 10.1002/0471141755.ph1205s22

Current Protocols in Pharmacology

Current Protocols in Pharmacology

How to Cite

Münk, C. and Landau, N. R. 2003. Production and Use of HIV-1 Luciferase Reporter Viruses. Current Protocols in Pharmacology. 22:12.5:12.5.1–12.5.12.

Author Information

  1. The Salk Institute for Biological Studies, La Jolla, California

Publication History

  1. Published Online: 1 NOV 2003
  2. Published Print: SEP 2003


This unit describes the production and use of HIV-1 luciferase reporter viruses. These viruses are used to rapidly and accurately quantify HIV-1 in cell culture. Protocols are also presented for screening and characterization of small molecule inhibitors of HIV-1 entry into cells.


  • reporter virus;
  • entry;
  • infection;
  • envelope glycoprotein;
  • HIV-1;
  • luciferase