UNIT 12.11 Drug Testing in Cellular Chemotaxis Assays
Published Online: 1 JUN 2008
Copyright © 2008 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
Mellado, M., Martínez-A, C. and Rodríguez-Frade, J. M. 2008. Drug Testing in Cellular Chemotaxis Assays. Current Protocols in Pharmacology. 41:12.11:12.11.1–12.11.22.
- Published Online: 1 JUN 2008
- Published Print: JUN 2008
Described in this unit are methods for measuring the cell migration process. While cell adhesion protocols allow study of migrating cell interactions with the endothelial matrix, cellular migration assays permit analysis of directed cell movement towards a chemotactic gradient, both in vivo and in vitro. An in vitro cell invasion protocol is provided for analysis of the sum of the cell adhesion, migration, and invasion activities involved in tumor cell motility. Curr. Protoc. Pharmacol. 41:12.11.1-12.11.22. © 2008 by John Wiley & Sons, Inc.