UNIT 14.7 Application of Radiotherapy and Chemotherapy Protocols to Pre-Clinical Tumor Models
Published Online: 1 SEP 2007
Copyright © 2007 by John Wiley and Sons, Inc.
Lab Protocol Title
Current Protocols in Pharmacology
How to Cite
Burd, R. and Wachsberger, P. 2007. Application of Radiotherapy and Chemotherapy Protocols to Pre-Clinical Tumor Models. Current Protocols in Pharmacology. 38:14.7:14.7.1–14.7.24.
- Published Online: 1 SEP 2007
- Published Print: SEP 2007
This unit (1) provides background into understanding how agents that target specific molecules or receptors (molecular-targeted agents), in particular, agents affecting the tumor vasculature (perivasculature network in tumors), interact with and modify radiation therapy; (2) details factors affecting interpretation of results in murine tumor model experiments utilizing radiation therapy and drug combinations; and (3) provides specific protocols for the application of radiation therapy, both alone and in combination with chemotherapy and/or molecular-targeted agents. Curr. Protoc. Pharmacol. 38:14.7.1-14.7.24. © 2007 by John Wiley & Sons, Inc.
- radiation therapy;
- tumor models;
- tumor hypoxia;
- tumor growth delay;